Month: <span>January 2016</span>

FoodFun Science

Weird News Roundup: Strange Brew Part II

January 23, 2016September 1, 2016 Science UnfilteredLeave a comment

Back in October, we told you about the …unique way Oregon is brewing beer. That’s not the only way alcohol has grasped our attention recently.

Tagged 1800s,A. Keith & Son Brewery,Alcohol,Andrew MacIntosh,Auto-Brewery Syndrome,BAC,Beer,Beer Bottle,Blood Alcohol Content,Blood Alcohol Level,Booze,Bottle,Brew,Brewing,Christopher Reynolds,CNN,Dalhousie University,Drink,Drinking,Drunk,DUI,Endogenous Ethanol Fermentation,Exercise,Gym,Halifax,Halifax Harbor,Hops,Inverse,Jon Crouse,Mediterranean Diet,Moderation,New York,Nova Scotia,NPR,Sodium,Spirits,Sports Drink,Stillwell Beer Bar,Sugar,Unintentional Drunkness

Sample Preparation

SPE Method Validation Terms: Precision and Accuracy

January 19, 2016September 1, 2016 Science Unfiltered2 Comments

In the heart of every good chromatographer is a solid understanding of the most crucial vocabulary. For those practicing solid phase extraction, precision and accuracy are fundamental components to their craft.

Tagged Accuracy,Accuracy and Precision,Accurate,Analyst,Analytical,Analytical Chemistry,Analytical Science,Analyze,Bio,Bioanalytical,Chemistry,Chromatography,Compound Analysis,Concentration,FDA,High,Inter-Day,Intermediate Precision,Intra-Day,LLOQ,Low,Low Medium High,Lower Limit of Quantitation,Medium,Method,Method Development,Method Validation,Pharma,Pharmaceutical,Phenomenex,Precise,Precision,Quantitation,Relative Standard Deviation,Repeat,Repeatability,Reproduce,Reproducibility,RSD,Science,Separation,Separation Science,Separation Sciences,Solid Phase Extraction,SPE,SPE Method Validation,SPE Method Validation Terms,SPE Terms,Terms,Validate,Validation,Variation,Variations,Vocabulary

Liquid Chromatography (LC)Technical Tips

Technical Tip: Principle HPLC Conditions for LC/MS

January 18, 2016May 16, 2017 Science UnfilteredLeave a comment

High-performance (or pressure) liquid chromatography, more commonly known as HPLC, can be a useful tool to assist in the improvement or simplicity of mass spectral detection and analysis.

Tagged Absolute Solvent Flow,Acetic,Acetic Acid,Acetonitrile,Acid,Acids,Alkylsulfonates,Analysis,Analyte,Analytes,Analyze,Buffer,Buffers,Challenge,Challenges,Chromatogram,Chromatograms,Chromatographer,Chromatographers,Chromatographic,Chromatography,Column,Columns,Desolvation,Detection,Eluant,Eluent,Elution,Evaporation,Flow,Flow Rate,Formic,Formic Acid,High Performance Liquid Chromatography,High Pressure Liquid Chromatography,HILIC,HPLC Column,HPLC System,HPLC Systems,Hydrophilic Interaction Liquid Chromatography,Ion,Ion-Pair Reagent,Ion-Pair Reagents,Ion-Source,Ion-Suppression Zone,Ionizable,LC,LC/MS,LC/MS/MS,Liquid Chromatography,Liquid Chromatography (LC),Mass Spec,Mass Spectral,Mass Spectrometry,Mobile Phase,Non-Volatile,Organic,Organic Acid Buffers,Parameters,Peak,Peak Shape,Peak Shapes,Peaks,pH,Phase,Phases,Phenomenex,Polar,Reversed Phase,Science,Sensitivity,Separation,Separation Sciences,Silica,Solvent,Stationary Phase,System,Systems,TEA,TFA,UHPLC,Void,Volatile,Volatile Acidic Ion-Pair Reagent,Volatile Basic Ion-Pair Reagent,Volatility

Fun ScienceLiquid Chromatography (LC)Pharma / Biopharma

Allowable Adjustments to Pharmacopoeia Methods: Simplified Version

January 8, 2016August 16, 2017 Science UnfilteredLeave a comment

Effective August 2014, the United States Pharmacopoeia and the National Formulary published the latest revision to General Chapter on Chromatography that further clarifies what “allowable adjustments” can be made to USP methods without having to revalidate these methods.