The Buck Institute is the nation’s first independent research facility focused solely on understanding the connection between aging and chronic disease in pursuit of the Mission to increase the healthy Continue Reading
Increase Production Economy Using Aggressive Wash Conditions
A significant cost in preparative purification processes is down time during sorbent replacement. Sorbents are typically replaced when washing procedures no longer restore adequate performance or when backpressure remains high. Continue Reading
The Effects of Changing Column Inner Diameter on LC-MS Applications-Part 4
Part 4: Putting Our Interpretation to the Test Guest Author: Dr. Jeff Layne Welcome back to our final installation of this blog series on the effect of column inner diameter Continue Reading
Natural Lithium in Tap Water Could Protect Against Dementia
Dementia is one of the leading causes of disability in the elderly worldwide, with 9.9 million new cases happening every year. And yet, there is still not a lot known Continue Reading
Chiral Chromatography and the Pharmaceutical Industry
Guest Author: Abraham Becerra Since its discovery, chiral chemistry has played a pivotal role in how scientists examine novel compounds. This unique characteristic describing a molecule’s geometry in three-dimensional space Continue Reading
Complementary Selectivity for Peptide Analysis
Guest Author: Dr. Jeff Layne It seems like more and more companies are shifting their focus towards the development of biopharmaceuticals these days. Peptide analysis, whether it be intact therapeutic Continue Reading
Utilizing Mobile Phase pH to Maximize Preparative Purification Efficacy
Preparative chromatography is a specialized subset of chromatography, where the goal is to purify a target analyte (or analytes in some cases) from a complex mixture of crude sample. The Continue Reading
Do You Know the Difference Between Viewing the Sun Normally and a Solar Eclipse?
You might not have heard anything about it, but there was a solar eclipse today. In fact, it was the first time in U.S. history that a solar eclipse traveled Continue Reading
Chemistry Just Made Drinking Whiskey, A Splash Better
Many bartenders may tell you that adding a splash of water to your drink of whiskey will make it taste better. Those with an old school track of mind, may Continue Reading
Doing HPLC Method Development for Monoclonal Antibody Aggregates? Wait a “SEC”!
By Guest Author: Brian Rivera Contrary to popular belief, size exclusion chromatography (SEC) isn’t straightforward. However, it should be—it’s a non-absorptive separation, right? Just look up an SEC column’s calibration Continue Reading