How to Achieve Advanced Multi-modal LC Selectivity

Looking to achieve an advanced multi-modal LC selectivity for you next analysis? Look no further than Kinetex® PS C18. Designed for every scientist who are looking for:

  • Enhanced Retention for Polar Basic Compounds
  • 100% Aqueous Stability
  • Available in 2.6 µm for UHPLC and HPLC

By making the switch from fully porous to core-shell particles, labs gain instant access to increased productivity, improved chromatographic results, easy method transferability, and significant cost savings.

Thrive with Kinetex Core-Shell Technology

But don’t take our word for it! Check out our application notes of how Kinetex PS C18 performed compared to a conventional fully porous UHPLC columns and achieves your desired LC selectivity. Click the link or image below to keep reading: CLICK HERE

Summary of “Kinetex® 2.6µm PS C18 Core-Shell Column’s Chromatographic Performance and Unique Reversed Phase Selectivity in Comparison to a Conventional Fully Porous UHPLC Column”

“Our scientists wanted to investigate the Kinetex 2.6µm PS C18 HPLC/UHPLC column’s improved chromatographic performance and unique multi interaction selectivity when applied to a screen of 36 tricyclic antidepressants. Both columns tested were of the same dimension (100 x 2.1mm) and ran under identical conditions, on the same UHPLC system, and during the same period of time. The gradient consisted of Water with 0.1% Formic acid as the weak solvent and Acetonitrile with 0.1% Formic acid as the strong organic solvent. A flow rate of 0.5mL/min was used, and the column heater was set to an ambient temperature of 25°C. An Agilent® 1200 HPLC system was used for the investigation with a SCIEX™ API 4000™ mass spectrometer (MS) for detection. The Kinetex PS C18 is a USP classified L1 column, that provides both a unique polar and non-polar selectivity as well as 100% aqueous stability.”

New Core-shell Column to improve LC Selectivity

Have questions or looking for assist for your next method development? Reach out to our Technical Experts 24/7 with Live Chat! Click the link to start chatting today: CLICK HERE

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