Synthetic Oligonucleotides – Analysis of Their Complex Structure

synthetic oligonucleotides

Guest Author – Helen Whitby, PhD., Technical Specialist Synthetic oligonucleotides are promising therapeutic agents and their characterization is fundamental to their success. However, various impurities either product-related or arising from Continue Reading

Chiral Compounds – What to Know & How They Relate to Chromatography

chiral compounds and how they relate to chromatography

Guest Author – Ryan Splitstone, Product Marketing Manager Chemical isomers originate from the same chemical formula but differ in the spatial arrangement of their chemical functional groups or bond order Continue Reading

Oligonucleotides – What Are They and Why Are They of Interest

oligonucleotides

Guest Author – Helen Whitby, PhD., Technical Specialist Oligonucleotides can be used to control gene expression and this makes them of increasing interest in the move to control disease. Oligonucleotides Continue Reading

HPLC Column Lifetime – Knowing When It Is Time to Say Goodbye

HPLC Column Lifetime

Guest Author – Dr. Helen Whitby, Technical Specialist Letting go of your favorite column can be hard to do, so when is it really time to say goodbye? Below are Continue Reading

Mobile Phase Preparation – Steps to Take for Ideal Analysis

components of mobile phase

Guest Author – Technical Expert Genevieve Hodson Liquid Chromatography is reliant upon a accurately made mobile phase. Many chromatographic problems can be attributed to an incorrectly prepared mobile phase. Contamination Continue Reading

Tips on Installing an Ion-Exclusion Column and Extending Column Lifetime

Extending ion-exchange column lifetime

Guest Author: Grace Guo, Phenomenex Technical Specialist Ion-exclusion columns, such as the Phenomenex Rezex column, have been widely used on the analysis of sugars and organic acids. The aqueous based Continue Reading