Guest Author: Zara Jalali What is PFAS? PFAS is an abbreviation for per- and polyfluoroalkyl substances which are a large family of man-made chemicals that contain a carbon and fluorine Continue Reading
The Importance of a Well Prepared Mobile Phase Explained
Guest Author – Helen Whitby, PhD A buffer is an AQUEOUS solution containing a weak acid and its conjugate base (or a weak base and its conjugate acid). The pH of a buffer solution changes Continue Reading
HILIC Technical Tip for Stronger Analytical Methods
Technical Tip: Engineering successful analytical methods using HILIC as an alternative retention mechanism Overview: This technical tip will outline hydrophilic interaction chromatography (or hydrophilic interaction liquid chromatography, HILIC) as an alternative retention mechanism that is particularly effective for LC-MS. Continue Reading
LC Tubing – How to Set Bend Radius with SecurityLINK
Gust Author – Genevieve Hodson – Senior Technical Specialist Liquid chromatography (LC) tubing can be made from a few different types of materials depending on the needs of the laboratory. Continue Reading
Comparison of Micro LC Columns with Additional LC-MS/MS Insights
Article Written Based on Technical Application by – Roxana Eggleston-Rangel, Ryan Splitstone, and Jason Anspach, PhD. Micro LC uses columns with internal diameters (I.D.) that are typically within the range Continue Reading
Technical Tip – How to Improve Your Micro LC Column’s Performance
Guest Author – Helen Whitby, PhD, Technical Specialist Micro LC columns offer chromatographers the opportunity to improve sensitivity or use lower flow rates due to their smaller internal diameter. The Continue Reading
Column Temperature – How to Maintain Accuracy and Stability
Guest Author – Genevieve Hodson, Technical Specialist It is common practice to leave LC columns at ‘room temperature’, or ambient temperature conditions when running routine analytical methods. So why do Continue Reading
Genotoxic Nitrosamine Analysis Resource Center Site
Have you explored our Genotoxic Nitrosamine Resource Center? Take a minute today to peruse the site which covers a range of resources from app notes to webinars, to tools Phenomenex Continue Reading
Synthetic Oligonucleotides – Analysis of Their Complex Structure
Guest Author – Helen Whitby, PhD., Technical Specialist Synthetic oligonucleotides are promising therapeutic agents and their characterization is fundamental to their success. However, various impurities either product-related or arising from Continue Reading
Chiral Compounds – What to Know & How They Relate to Chromatography
Guest Author – Ryan Splitstone, Product Marketing Manager Chemical isomers originate from the same chemical formula but differ in the spatial arrangement of their chemical functional groups or bond order Continue Reading