Comparison of Micro LC Columns with Additional LC-MS/MS Insights

Micro LC columns

Article Written Based on Technical Application by – Roxana Eggleston-Rangel, Ryan Splitstone, and Jason Anspach, PhD. Micro LC uses columns with internal diameters (I.D.) that are typically within the range Continue Reading

Technical Tip – How to Improve Your Micro LC Column’s Performance

How to improve your Micro LC column's performance

Guest Author – Helen Whitby, PhD, Technical Specialist Micro LC columns offer chromatographers the opportunity to improve sensitivity or use lower flow rates due to their smaller internal diameter. The Continue Reading

Column Temperature – How to Maintain Accuracy and Stability

column temperature

Guest Author – Genevieve Hodson, Technical Specialist It is common practice to leave LC columns at ‘room temperature’, or ambient temperature conditions, when running routine analytical methods. So why do Continue Reading

Synthetic Oligonucleotides – Analysis of Their Complex Structure

synthetic oligonucleotides

Guest Author – Helen Whitby, PhD., Technical Specialist Synthetic oligonucleotides are promising therapeutic agents and their characterization is fundamental to their success. However, various impurities either product-related or arising from Continue Reading

Chiral Compounds – What to Know & How They Relate to Chromatography

chiral compounds and how they relate to chromatography

Guest Author – Ryan Splitstone, Product Marketing Manager Chemical isomers originate from the same chemical formula but differ in the spatial arrangement of their chemical functional groups or bond order Continue Reading

Oligonucleotides – What Are They and Why Are They of Interest

oligonucleotides

Guest Author – Helen Whitby, PhD., Technical Specialist Oligonucleotides can be used to control gene expression and this makes them of increasing interest in the move to control disease. Oligonucleotides Continue Reading

HPLC Column Lifetime – Knowing When It Is Time to Say Goodbye

HPLC Column Lifetime

Guest Author – Dr. Helen Whitby, Technical Specialist Letting go of your favorite column can be hard to do, so when is it really time to say goodbye? Below are Continue Reading