Our previous technical tip spoke about silylation reagents that may be used to derivatize a range of polar, acidic, and basic analytes to improve volatility and peak shape during gas chromatography. Silylating Continue Reading
Mycotoxins in Cannabis – Exploring More Comprehensive Testing
Reprinted with the kind permission of International Labmate Ltd – first printed in International Labmate, November 2020, Volume45 Issue 7 – www.intlabmate.com The Movement Towards More Comprehensive Testing of Mycotoxins in Cannabis Guest Author Continue Reading
Derivatization in Gas Chromatography (GC) Explained
Gas Chromatography is a fantastic technique to achieve exceedingly sharp peaks and resolutions within a complex mixture of analytes. But each analyte must be volatile to facilitate GC analysis. Derivatization Continue Reading
The Importance of a Well Prepared Mobile Phase Explained
Guest Author – Helen Whitby, PhD A buffer is an AQUEOUS solution containing a weak acid and its conjugate base (or a weak base and its conjugate acid). The pH of a buffer solution changes Continue Reading
HILIC Technical Tip for Stronger Analytical Methods
Technical Tip: Engineering successful analytical methods using HILIC as an alternative retention mechanism Overview: This technical tip will outline hydrophilic interaction chromatography (or hydrophilic interaction liquid chromatography, HILIC) as an alternative retention mechanism that is particularly effective for LC-MS. Continue Reading
LC Tubing – How to Set Bend Radius with SecurityLINK
Gust Author – Genevieve Hodson – Senior Technical Specialist Liquid chromatography (LC) tubing can be made from a few different types of materials depending on the needs of the laboratory. Continue Reading
Technical Tip – How to Improve Your Micro LC Column’s Performance
Guest Author – Helen Whitby, PhD, Technical Specialist Micro LC columns offer chromatographers the opportunity to improve sensitivity or use lower flow rates due to their smaller internal diameter. The Continue Reading
Size Exclusion Chromatography – A Tool For Antibody Aggregate Analysis
Guest Author – Namrata Saxena, Technical Specialist – Phenomenex Asia/Pacific Monoclonal Antibodies are large and complex biomolecules which falls in the prominent section of biotherapeutic drugs market. The complex structure Continue Reading
Nitrogen for Fast GC Analysis? Let’s Narrow Down this Idea
Guest Author – Zachary Woodward, Technical Specialist – Phenomenex USA Shorter run-times, sharper peaks, improved resolution, and low costs of carrier gas…we want it all! These goals can seem at Continue Reading
Column Temperature – How to Maintain Accuracy and Stability
Guest Author – Genevieve Hodson, Technical Specialist It is common practice to leave LC columns at ‘room temperature’, or ambient temperature conditions when running routine analytical methods. So why do Continue Reading