What is Bisphenol A (BPA) and How Does It Affect You?


By Scott Krepich, Food and Environmental Application Scientist The chemical bisphenol A (BPA) is used in the production of some plastics, many of which are utilized in water bottles and Continue Reading

What is HILIC Separation? What Does It Mean For You?

HILIC Separation

By Scott Krepich, Food and Environmental Application Scientist Hydrophilic Interaction Chromatography (HILIC) is a variant of normal-phase liquid chromatography that partly overlaps with other chromatographic applications such as ion-chromatography and Continue Reading

Best and Worst Organic Solvents to Use in LC

There are several critical characteristics to take into consideration when choosing the appropriate organic solvent to use in liquid chromatography. For example, high viscosity solvents may produce backpressures that are too high for the HPLC system used.

What the HILIC is HILIC?

Hydrophilic interaction liquid chromatography (HILIC) is a chromatographic mode used mainly for the separation of polar compounds that are too hydrophilic to be retained in a reversed phase column.

Technical Tip: Bulk HPLC Sorbent Storage and Cleaning for Reuse

In the spirit of frugality, process chromatographers often want to save and store their media for future use. There are steps one can take to store bulk resins for short term and long term use, though it’s worth noting that the media will not last forever.

Technical Tip: Principle HPLC Conditions for LC/MS

High-performance (or pressure) liquid chromatography, more commonly known as HPLC, can be a useful tool to assist in the improvement or simplicity of mass spectral detection and analysis.

Technical Tip: Protein Precipitation

protein precipitation

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