antibody drug conjugates Archives - SCIENCE UNFILTERED

https://www.googleoptimize.com/optimize.js?id=OPT-T3HPS7B

FeaturedSample PreparationTechnical Tips

Size Exclusion Chromatography – A Tool For Antibody Aggregate Analysis

September 24, 2020September 30, 2020 Science UnfilteredLeave a comment

size exclusion chromatography as a tool for antibody analysis

Guest Author – Namrata Saxena, Technical Specialist – Phenomenex Asia/Pacific Monoclonal Antibodies are large and complex biomolecules which falls in the prominent section of biotherapeutic drugs market. The complex structure Continue Reading

Tagged Antibodies,Antibody,antibody drug conjugates,drug antibody ratio,gel filtration chromatography,Gel Permeation Chromatography,GFC,monoclonal antibodies,monoclonal antibody,post-translational modifications,sec,size exclusion,size exclusion chromatography

FeaturedLiquid Chromatography (LC)Pharma / BiopharmaTechnical Tips

What is Drug Antibody Ratio and How Does It Relate to Biotherapeutics?

June 5, 2018 Science UnfilteredLeave a comment

DAR: Drug Antibody Ratio

Meet James Song, R&D Research Scientist– Bioseparations James has over 20 years of experience in the arena of biotechnology and has a wealth of experience in the fields of diagnostic Continue Reading

Tagged adc,ADC characterization,antibody drug conjugates,biodistribution,biopharm,biopharmaceuticals,bioseparations,biotherapeutics,Chemistry,DAR,drug antibody ratio,drug conjugated,HIC,HPLC,HPLC Methods,HPLC techniques,hydrophobic interaction chromatography,lc-ms,LC-MS/MS,lysine,pharmacokinetics,research scientist,Reversed Phase,UV-Vis,UV-Vis spectroscopy

FeaturedLiquid Chromatography (LC)Pharma / BiopharmaTechnical Tips

Is Your LC Column for Biologics Analysis, Truly Bio-Inert?

April 24, 2018April 24, 2018 Science UnfilteredLeave a comment

Let’s talk about column priming and how to address this common concern Guest Author: Chad Eichman, Ph.D., Biopharmaceutical Industry Manager With the emerging trend of biotherapeutics in the pharmaceutical industry, Continue Reading

Tagged ADCs,antibody drug conjugates,bio-inert,biologics analysis,biotherapeutics,BioTi,bovine serum albumin,BSA,column priming,core-shell particles,HPLC,HPLC backpressures,large molecules,mAbs,monoclonal antibodies,nickel alloy,organic polymer tubes,PEEK,PEEK Tubes,pharmaceutical industry,polyether ether ketone,protein properties,sec,size exclusion chromatography,titanium,UHPLC sub-2 μm

FeaturedPharma / Biopharma

ADCs-Magic Bullets, Failed Drugs, and Heterobifunctional Linkers

May 31, 2017November 28, 2017 Science Unfiltered1 Comment

ADCs

Guest Author: Brian Rivera, Product Manager: Bio Separations Over a hundred years ago, Nobel Prize laureate, Paul Ehrlich, envisioned a drug which could kill microbes but not harm the body, Continue Reading

Tagged adc,antibody drug conjugates,biophama,Cancer,chemotherapy alternatives,HPLC,monoclonal antibodies,paul ehrlich,Pharmacology,small molecules,UHPLC

Close