A Comparison of Various Core-Shell C18 Phases for Method Development

When performing reversed phase LC separations, there is a natural tendency of method developers to reach for the most commonly used phase—a C18. However, there are so many different variations of C18 phases available to method developers that it often becomes difficult to choose a C18 column that one had Continue Reading

What is Core-shell and Superficially Porous Technology?

Guest Author: Technical Specialist, Ann Montross Silica media in HPLC columns were originally irregular shaped particles of silica. Then silica based HPLC columns moved to the traditionally filled, fully porous spherical particles of silica that offered improvements in chromatography over irregular shaped particles. Figure 1: Fully Porous Particles As the Continue Reading

Kinetex HPLC/UHPLC Columns Win the Gold Seal of Quality from Leading Industry Publication, SelectScience

    Torrance, Calif. (July, 2017) – Phenomenex Inc, global leader in the research, design, and manufacture of advanced technologies for the separation sciences, announced today that its Kinetex® Core-Shell HPLC/UHPLC columns have won the Gold Seal of Quality by SelectScience, an industry leading online publication. The SelectScience® Gold Seal Continue Reading

Webinar Highlights – UHPLC: Small Particle Solutions for Big Chromatography Challenges

Senior Field Application Scientist Scott Krepich answers your questions on UHPLC column selection and shares industry-specific tips In this free webinar, Scott Krepich, Senior Field Application Scientist, Phenomenex Inc., gave an informative presentation on column selection for UHPLC and shared industry-specific tips on method screening and development. Read on for Continue Reading

Symbiosis of Core-Shell and Fully Porous Particles: Implementing Both for Better HPLC and UHPLC Results

(Via LCGC North America) Learn to capitalize on the advantages of both core-shell and thermally modified fully porous stationary phase media to expand the options for HPLC and UHPLC method development. High performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography(UHPLC) method development options can be extended significantly by tapping Continue Reading

Milton’s Tricks, Treats, and Technical Guides

You’ve worked so hard crafting the perfect costume, decorating your home, and sneaking chocolate from your kids, we decided to treat you to the best technical guides this Halloween.

Technical Tip: Peak Apex Flattening

Peak shape issues at the apex of a peak are typically related to detector saturation. This symptom can be observed as flattening and/or noise at the peak apex.

Cold and Flu Season: What’s Hugging Got to Do With It?

Valentine’s Day is approaching, love is in the air, and recent freezing temperatures make for perfect cuddling conditions. How appropriate, then, that today—January 21—is National Hugging Day!