Technical Tip: Engineering successful analytical methods using HILIC as an alternative retention mechanism Overview: This technical tip will outline hydrophilic interaction chromatography (or hydrophilic interaction liquid chromatography, HILIC) as an alternative retention mechanism that is particularly effective for LC-MS. Continue Reading
Metabolomics and Autism: Can Cross-linked Polyamine HPLC Columns Change Lives?
Chromatography has the ability to impact lives more than many think. Brian Rivera discovers this through his pursuit for more autism research for his son, Micah. By: Brian Rivera, Bioseparations Continue Reading
What is HILIC Separation? What Does It Mean For You?
By Scott Krepich, Food and Environmental Application Scientist Hydrophilic Interaction Chromatography (HILIC) is a variant of normal-phase liquid chromatography that partly overlaps with other chromatographic applications such as ion-chromatography and Continue Reading
What the HILIC is HILIC?
Hydrophilic interaction liquid chromatography (HILIC) is a chromatographic mode used mainly for the separation of polar compounds that are too hydrophilic to be retained in a reversed phase column.
Technical Tip: Principle HPLC Conditions for LC/MS
High-performance (or pressure) liquid chromatography, more commonly known as HPLC, can be a useful tool to assist in the improvement or simplicity of mass spectral detection and analysis.
Technical Tip: Ion-Pairing Agents
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