Tag: <span>Ion Exchange</span>

FeaturedLiquid Chromatography (LC)Technical Tips

Tips on Installing an Ion-Exclusion Column and Extending Column Lifetime

November 13, 2019November 13, 2019 Science UnfilteredLeave a comment

Guest Author: Grace Guo, Phenomenex Technical Specialist Ion-exclusion columns, such as the Phenomenex Rezex column, have been widely used on the analysis of sugars and organic acids. The aqueous based Continue Reading

Tagged extend column lifetime,Ion Exchange,Ion Exclusion,ion-exchange column,Ion-Exclusion Chromatography,Mobile Phase,Rezex,sulfonated styrene diviylbenzene

FeaturedLiquid Chromatography (LC)

Protein Therapeutics and the Best Methods to Analyze Them

January 4, 2019January 4, 2019 Science UnfilteredLeave a comment

Author: Chad Eichman, PhD – BioPharmaceutical Global Marketing Manager What are protein therapeutics / monoclonal antibodies? Protein therapeutics, specifically monoclonal antibodies (mAbs), have emerged as the most marketed biologic drug Continue Reading

Tagged biopharm,biopharmaceutical glossary,biopharmaceutical terms,biopharmaceuticals,cation ion exchange,charge variant analysis,CVA,heterogeneity data,HPLC/UHPLC,iCIEF,IEX,imaging capillary isoelectric,Ion Exchange,ion exchange chromatography,Liquid Chromatography,Liquid Chromatography (LC),liquid liquid extraction,mAbs,monoclonal antibodies,Pharmaceutical,pharmaceutical industry,Pharmaceuticals,protein therapeutic,protein therapeutics,SCX,strong cation exchange,titanium hardware,UHPLC,UHPLC Column,UHPLC instruments,UHPLC sub-2 μm,UHPLC System,WCX,WCX column,WCX Ion-Exchange Column,Weak cation exchange

FeaturedLiquid Chromatography (LC)Pharma / BiopharmaTechnical Tips

Sitting with Scientists: Srinivasa Rao, PhD. – The Ion Exchange Guru

October 16, 2018October 19, 2018 Science UnfilteredLeave a comment

Interview with Srinivasa Rao, PhD., Senior Scientist at Phenomenex An accomplished scientist in monoclonal antibody and protein analytical development, purification, and characterization, and has also designed columns, applications, and method Continue Reading

Tagged Albert Einstein College,Albert Einstein College of Medicine,amyloid proteins,biochemistries,Biochemistry,bioZen,carbohydrates,cation ion exchange,cation-exchange chromatography,characterization,DNA,Dr. Rao,FDA,IEX,IEX techniques,Ion Exchange,isoelectric points,mAbs,micro-heterogeneity,monoclonal antibody,peptides,protein analytical development,Proteins,Purification,Ranbaxy Laboratories,Sankara Eye Foundation,sialylation,Silicon Andhra,Srinivasa Rao,USFDA,WCX,WCX Ion-Exchange Column

FeaturedLiquid Chromatography (LC)Technical Tips

What is HILIC Separation? What Does It Mean For You?

February 15, 2018June 20, 2018 Science UnfilteredLeave a comment

La cromatografía de interacción hidrofílica

By Scott Krepich, Food and Environmental Application Scientist Hydrophilic Interaction Chromatography (HILIC) is a variant of normal-phase liquid chromatography that partly overlaps with other chromatographic applications such as ion-chromatography and Continue Reading

Tagged Acetonitrile,Bioanalytical,HILIC,HILIC elution,HILIC Separation,Hydrophilic,Hydrophilic Interaction Liquid Chromatography,Ion Exchange,LC-MS/MS,Normal Phase,Polar Analytes,Reversed Phase

Liquid Chromatography (LC)Technical TipsUncategorized

Technical Tip: Peak Apex Flattening

February 19, 2016April 15, 2016 Science UnfilteredLeave a comment

Peak shape issues at the apex of a peak are typically related to detector saturation. This symptom can be observed as flattening and/or noise at the peak apex.