Can an UHPLC Column Have Too Much Efficiency?

Is 100% aqueous stability and unique polar selectivity not enough to convince you to try Luna Omega? Well, here is another equally-compelling reason Guest Author: Dr. Jeff Layne You Can Never Have Too Much Efficiency! The efficiency of a column is a measurement of the amount of band broadening that Continue Reading

Selectivity for Polar Acids

Guest Author: Dr. Jeff Layne Is super-high efficiency and 100 % aqueous stability not enough to convince you to try Luna® Omega UHPLC Columns? Well then, how about a unique selectivity for polar acidic molecules? Selectivity for Polar Acids is Sweet! Developing robust methods for the analysis of small, polar Continue Reading

Rock Out to Toxicology’s Greatest Hits

This year’s hottest mix is a playlist that will rock on for centuries to come. It has been praised as the album of the year by The Rolling Chromatography* and The New York Toxicology Times* calls it a “massive hit!” Let’s go through the tracks to have a quick listen Continue Reading

Gila Monster Saliva Could Save Lives: A Simplified Purification of Exenatide Peptide

Is Gila Monster's Saliva poisonous

Ever wonder what the inside of the venomous Gila Monster’s mouth was like? Yeah, we did too. Exenatide, a synthetic version of excendin-4, is a hormone found in the saliva of the Gila Monster. A glucagon-like peptide-1 agonist, Exenatide was approved in April 2005 for the treatment of diabetes mellitus Continue Reading

Milton’s Tricks, Treats, and Technical Guides

You’ve worked so hard crafting the perfect costume, decorating your home, and sneaking chocolate from your kids, we decided to treat you to the best technical guides this Halloween.

The Man, The Myth, The Milton: Meet our Newest Teammate!

Full-time chromatography enthusiast, analyst, and guest blogger (with devilishly good looks).

The Phenomenex Story: Part II

Richard Thomas is Chief Scientific Officer at Precision Diagnostics. Sonia Nicholas, Associate Editor at Select Science, spoke to Richard to learn more about his work and the technology that he uses in his laboratory.

Best and Worst Organic Solvents to Use in LC

There are several critical characteristics to take into consideration when choosing the appropriate organic solvent to use in liquid chromatography. For example, high viscosity solvents may produce backpressures that are too high for the HPLC system used.

What the HILIC is HILIC?

Hydrophilic interaction liquid chromatography (HILIC) is a chromatographic mode used mainly for the separation of polar compounds that are too hydrophilic to be retained in a reversed phase column.

10 Questions You’ve Always Wanted to Ask About LC

Want to submit a question? Leave it in the comments!