Can an UHPLC Column Have Too Much Efficiency?

Is 100% aqueous stability and unique polar selectivity not enough to convince you to try Luna Omega? Well, here is another equally-compelling reason Guest Author: Dr. Jeff Layne You Can Never Have Too Much Efficiency! The efficiency of a column is a measurement of the amount of band broadening that Continue Reading

Selectivity for Polar Acids

Guest Author: Dr. Jeff Layne Is super-high efficiency and 100 % aqueous stability not enough to convince you to try Luna® Omega UHPLC Columns? Well then, how about a unique selectivity for polar acidic molecules? Selectivity for Polar Acids is Sweet! Developing robust methods for the analysis of small, polar Continue Reading

Why 100% Aqueous Stability is Important and Fun

Guest Author: Dr. Jeff Layne As the LC Product Manager for Phenomenex, one of the most common requests I get is to explain, in simple and practical terms, the features and benefits of our various LC products. Phenomenex has A LOT of different LC products after being in the business Continue Reading

Rock Out to Toxicology’s Greatest Hits

This year’s hottest mix is a playlist that will rock on for centuries to come. It has been praised as the album of the year by The Rolling Chromatography* and The New York Toxicology Times* calls it a “massive hit!” Let’s go through the tracks to have a quick listen Continue Reading

Selecting the Right Column for Your Reversed Phase Method

Selecting the right column for your reversed phase method isn’t always easy. We wanted to help in the decision-making process by breaking down the different steps you’ll need to consider when selecting your column. For a full in depth look into the selection process see our Ultimate Guide to HPLC/UHPLC Continue Reading

Webinar Highlights – UHPLC: Small Particle Solutions for Big Chromatography Challenges

Senior Field Application Scientist Scott Krepich answers your questions on UHPLC column selection and shares industry-specific tips In this free webinar, Scott Krepich, Senior Field Application Scientist, Phenomenex Inc., gave an informative presentation on column selection for UHPLC and shared industry-specific tips on method screening and development. Read on for Continue Reading

Symbiosis of Core-Shell and Fully Porous Particles: Implementing Both for Better HPLC and UHPLC Results

(Via LCGC North America) Learn to capitalize on the advantages of both core-shell and thermally modified fully porous stationary phase media to expand the options for HPLC and UHPLC method development. High performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography(UHPLC) method development options can be extended significantly by tapping Continue Reading

Jeff Tries Cannabis Part 4: Method Development

Part 4: A New Hope Guest Author: Jeff Layne Hey everyone, and welcome back to the cannabis method development series. So far in our quest to separate the twelve cannabinoids, we have messed around with gradient rates, mobile phase modifiers, and flow rates, yet have only been able to successfully Continue Reading

Gila Monster Saliva Could Save Lives: A Simplified Purification of Exenatide Peptide

Is Gila Monster's Saliva poisonous

Ever wonder what the inside of the venomous Gila Monster’s mouth was like? Yeah, we did too. Exenatide, a synthetic version of excendin-4, is a hormone found in the saliva of the Gila Monster. A glucagon-like peptide-1 agonist, Exenatide was approved in April 2005 for the treatment of diabetes mellitus Continue Reading