Upgrade Your Existing 624plus Phase Today Guest Author: Ramkumar Dhandapani, Ph.D.- Global Product Manager, Gas Chromatography While 624plus is an EPA method that was popular in environmental laboratories to analyze volatile organic Continue Reading
Large vs Small Organic Molecules in Biopharmaceuticals
Biopharmaceuticals have emerged as the next-gen of therapeutic (large and small) molecules in the pharmaceutical industry Guest Author: Chad Eichman, Ph.D., Biopharmaceutical Industry Manager The pharmaceutical industry has a long-standing Continue Reading
6 Reasons to CHOOSE Luna® Omega Instead of ACQUITY® BEH
What is Luna® Omega? Luna® is one of the most recognized HPLC brands on the market, delivering high efficiency, ruggedness, reproducibility and dependability for wide range of analyses. The new Continue Reading
What is USP Chapter 621?
The United States Pharmacopeia (USP) has defined the limits of “allowable adjustments” in USP General Chapter <621>, where revalidation is required if adjustment limits are exceeded. Even though this chapter Continue Reading
Transform Your HPLC and UHPLC Method Development Mindset on Analyzing Proteins— Including Monoclonal Antibodies!
A discussion of wide-pore/core-shell technology for monoclonal antibodies, method development considerations with wide-pore/core-shell columns, size exclusion chromatography (SEC) using sub-2 μm particles, and method optimization for SEC. (Webinar sneak peek) Continue Reading
SPE vs LLE: A Battle of Methods
An Improved SPE Clean Up and Recovery of Pharmaceutical Compounds from Plasma using Strata® -X In one corner, we have liquid-liquid extraction (LLE), which is perhaps the most established clean-up Continue Reading
What is Chiral?
What Exactly Does Chiral Mean? Chirality is a special physical property of a molecule which describes its geometry in three-dimensional space. Chiral molecules commonly consist of a carbon atom attached Continue Reading
Humanity in Science: Combating Counterfeit with Capillary Electrophoresis
The Humanity in Science Award was created in 2015 to recognize outstanding developments in science that could change human lives for the better. There were many runners-up who did (and do!) amazing things for humanity. Recently, The Analytical Scientist sat down with each of them to catch up, and find out how their ventures have progressed in the last 12 months.
SPE Method Validation Terms: Precision and Accuracy
In the heart of every good chromatographer is a solid understanding of the most crucial vocabulary. For those practicing solid phase extraction, precision and accuracy are fundamental components to their craft.