Technical Tip: Engineering successful analytical methods using HILIC as an alternative retention mechanism Overview: This technical tip will outline hydrophilic interaction chromatography (or hydrophilic interaction liquid chromatography, HILIC) as an alternative retention mechanism that is particularly effective for LC-MS. Continue Reading
Guest Author – Zachary Woodward, Technical Specialist We recently reviewed How Phase Ratio Can Shorten Run-Times While Preserving Resolution, and I would like to elaborate on the relevance of the Continue Reading
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For most reversed-phase solid phase extraction applications using a silica-based SPE media, cartridges are initially conditioned using an organic solvent such as methanol, followed by rinsing with water or a buffer.
Scientists aren’t perfect. Nobody is. In our Technical Tips, we can solve your most debilitating issues—from mechanics to methodology—together.
Scientists aren’t perfect. Nobody is. In our Technical Tips, we can solve your most debilitating issues—from mechanics to methodology—together.
Peaks in your chromatogram not attributed to the sample injected are commonly referred to as ghost peaks. Several problems can be the cause of ghost peaks manifesting, including: Late Continue Reading
