SPE vs LLE: A Battle of Methods

An Improved Clean Up and Recovery of Pharmaceutical Compounds from Plasma using Strata® -X In one corner, we have liquid-liquid extraction (LLE), which is perhaps the most established clean-up technique used in the chromatography field. Although it has been used for years, newer techniques with improved specificity towards particular analytes, Continue Reading

Milton’s Featured Method: Chlorinated Pesticides from Poultry Fat

Concerns surrounding pesticide contamination are not limited to fruits and vegetables. According to Toxics Action Center, pesticides are used almost everywhere: not only in agricultural fields, but also in homes, parks, schools, buildings, forests, and roads.

Milton’s Tricks, Treats, and Technical Guides

You’ve worked so hard crafting the perfect costume, decorating your home, and sneaking chocolate from your kids, we decided to treat you to the best technical guides this Halloween.

β-Gone β-Glucuronidase Removal FAQs

β-Gone β-Glucuronidase Removal 96-well plates and tubes are designed to target and remove β-glucuronidase from hydrolyzed urine samples without requiring additional time or method development. In a single step and in less than 1 minute, your hydrolyzed samples are ready for analysis.

Addressing Cannabis Research Challenges with Gas Chromatography

With marijuana decriminalization on the rise in the United States, many people might expect to see more sophisticated systems of labeling and identification in their newly sanctioned cannabis products. Easier said than done.

Poor Sample Recovery? You May Be Over-Drying

For most reversed-phase solid phase extraction applications using a silica-based SPE media, cartridges are initially conditioned using an organic solvent such as methanol, followed by rinsing with water or a buffer.

SPE Method Validation Terms: Precision and Accuracy

In the heart of every good chromatographer is a solid understanding of the most crucial vocabulary. For those practicing solid phase extraction, precision and accuracy are fundamental components to their craft.

Technical Tip: Optimizing Wash and Elution Protocols in SPE Method Development

Scientists aren’t perfect. Nobody is. In our Technical Tips, we can solve your most debilitating issues—from mechanics to methodology—together.

Technical Tip: Protein Precipitation

Scientists aren’t perfect. Nobody is. In our Technical Tips, we can solve your most debilitating issues—from mechanics to methodology—together.