Solid Phase Extraction Archives - SCIENCE UNFILTERED

FeaturedPharma / BiopharmaSample Preparation

SPE vs LLE: A Battle of Methods

May 17, 2017May 19, 2017 Science UnfilteredLeave a comment

An Improved Clean Up and Recovery of Pharmaceutical Compounds from Plasma using Strata® -X In one corner, we have liquid-liquid extraction (LLE), which is perhaps the most established clean-up technique Continue Reading

Tagged diclofenac,liquid liquid extraction,lle,Pharmaceutical,Plasma,Solid Phase Extraction

Food / BeverageGas Chromatography (GC)

Milton’s Featured Method: Chlorinated Pesticides from Poultry Fat

November 11, 2016February 28, 2017 Science UnfilteredLeave a comment

Concerns surrounding pesticide contamination are not limited to fruits and vegetables. According to Toxics Action Center, pesticides are used almost everywhere: not only in agricultural fields, but also in homes, parks, schools, buildings, forests, and roads.

Tagged Animal,Animal Feed,Animals,Bug Spray,Chemical,Chemicals,Chicken,Chickens,Chromatography,Crop,Crop Dusting,Crops,Environment,Environmental,Food,Food Quality,Food Safety,Gas Chromatography,Gas Chromatography (GC),GC,Laboratory,Method,Method Development,Pesticides,Phenomenex,Prevention.com,Sample Prep,Sample Preparation,Science,Separation,Separation Sciences,Solid Phase Extraction,SPE,Toxic,Toxics Action Center,Toxin,USDA,USDA-FSIS-ALP

EnvironmentalForensics / ToxicologyGas Chromatography (GC)Liquid Chromatography (LC)Pharma / Biopharma

Milton’s Tricks, Treats, and Technical Guides

October 31, 2016February 28, 2017 Science UnfilteredLeave a comment

You’ve worked so hard crafting the perfect costume, decorating your home, and sneaking chocolate from your kids, we decided to treat you to the best technical guides this Halloween.

Tagged Analysis,Biofuel,Biofuels,Capillary,Chiral,Column,Column Chromatography,Core-Shell,Environment,Environmental,Forensic,Forensic Toxicology,Fuel,Fuels,Gas Chromatography,GC,GC Column,Guide,Guides,Halloween,High Performance Liquid Chromatography,High Pressure Liquid Chromatography,HILIC,HPLC,HPLC Column,Industries,Industry,LC,LC Column,Liquid Chromatography,Milton,Pharma,Phenomenex,Sample Prep,Sample Preparation,Solid Phase Extraction,SPE,Technical Guide,Technical Guides,Technical Note,Technical Support,Technical Tip,Technical Tips,Test,Testing,Toxicology,Treat,Treats,Trick,Trick or Treat,Tricks,Troubleshooting,Vitamin

Forensics / ToxicologySample PreparationTechnical TipsUncategorized

β-Gone β-Glucuronidase Removal FAQs

September 26, 2016January 21, 2017 Science UnfilteredLeave a comment

β-Gone β-Glucuronidase Removal 96-well plates and tubes are designed to target and remove β-glucuronidase from hydrolyzed urine samples without requiring additional time or method development. In a single step and in less than 1 minute, your hydrolyzed samples are ready for analysis.

Tagged Absolute Recovery,Analyte,Analytes,Analytical Chemistry,Analytical Science,B-Gone,Beta-Glucuronidase,Beta-Gone,Beta-Gone Beta-Glucuronidase Removal Products,Chemistry,Chromatographer,Chromatographers,Chromatography,Column,Column Chromatography,Dilute,Dilute-and-Shoot,Dilution,Drug,Drugs,Drugs of Abuse,Enzyme,Enzymes,Extraction,Filter,Hydrolysis,Hydrolyze,Hydrolyzed,β-Glucuronidase,β-Glucuronidase Removal,β-Glucuronidase Removal Products,β-Gone,β-Gone β-Glucuronidase,β-Gone β-Glucuronidase Removal,β-Gone β-Glucuronidase Removal Products,Load,Loading,Matrix,Methanol,Pee,Phenomenex,Plate,Plates,Recovery,Sample,Sample Prep,Sample Preparation,Samples,Science,Sensitivity,Separation,Separation Sciences,Solid Phase Extraction,SPE,Technical Tips,Tube,Tubes,Urine

Food / BeverageGas Chromatography (GC)Uncategorized

Addressing Cannabis Research Challenges with Gas Chromatography

May 23, 2016September 1, 2016 Science Unfiltered2 Comments

With marijuana decriminalization on the rise in the United States, many people might expect to see more sophisticated systems of labeling and identification in their newly sanctioned cannabis products. Easier said than done.

Tagged Analytical Chemistry,Analytical Science,Brownie,Brownies,Cannabis,Cannabis Decriminalization,Cannabis Edible,Cannabis Edibles,Cannabis Legalization,Chemistry,Chromatograph,Chromatographer,Chromatographers,Chromatography,Column,Column Chromatography,Decriminalization,Edible,Edible Marijuana,Edibles,Flour,Food,Gas Chromatography,Gas Chromatography (GC),High Performance Liquid Chromatography,High Pressure Liquid Chromatography,Identification,Ingredient,Ingredients,Label,Labeling,Laboratory,Legalization,Liquid Chromatography (LC),Marijuana,Marijuana Decriminalization,Marijuana Edible,Marijuana Edibles,Marijuana Legalization,Mental Floss,Phenomenex,Pot,Pot Brownies,QuEChERS,Sample Prep,Sample Preparation,Science,Separation,Separation Sciences,Solid Phase Extraction,SPE,Sugar,Sugars,Sweets,Technical Tips,THC,Tobacco,Weed

Sample PreparationTechnical TipsUncategorized

Poor Sample Recovery? You May Be Over-Drying

February 23, 2016April 15, 2016 Science UnfilteredLeave a comment

For most reversed-phase solid phase extraction applications using a silica-based SPE media, cartridges are initially conditioned using an organic solvent such as methanol, followed by rinsing with water or a buffer.

Tagged Analyte,Analyte Loss,Analytes,Buffer,Buffers,C18,Cartridge,Cartridges,Centrifuge,Chromatogram,Chromatograms,Chromatographer,Chromatographers,Chromatography,Conditioning,Drying,Elution,Gravity,Gravity Flow,Loss of Analyte,Methanol,Over-Drying,Polymer,Polymeric,Pressure,QSP,Recovery,Reproducibility,Retention,Separation Sciences,Silica,Silica-Based,Solid Phase Extraction,Sorbent,Sorbents,SPE,Strata,Strata-X,Vacuum,Velocity

Sample PreparationUncategorized

SPE Method Validation Terms: Precision and Accuracy

January 19, 2016September 1, 2016 Science UnfilteredLeave a comment

In the heart of every good chromatographer is a solid understanding of the most crucial vocabulary. For those practicing solid phase extraction, precision and accuracy are fundamental components to their craft.