Tips to Maintain HPLC/UHPLC Systems and Improve Column Longevity

Column Longevity

Guest Author: Dr. Richard McAllister, Phenomenex UK With a new year, most of us have our new resolutions. Join a gym, get healthier, quit smoking, drink less, basically try to Continue Reading

Improve Performance of Strongly Basic Molecules

Guest Author: Dr. Jeff Layne One of the biggest challenges in reversed phase chromatography has always been maintaining acceptable peak shape for strongly basic analytes.  With typical silica-based reversed phase Continue Reading

Technical Tip: Peak Apex Flattening

Peak shape issues at the apex of a peak are typically related to detector saturation. This symptom can be observed as flattening and/or noise at the peak apex.