Tag: <span>SCIEX</span>

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How Nitrosamine Impurities Affect Your Blood Pressure Medicine

May 7, 2019May 7, 2019 Science UnfilteredLeave a comment

How nitrosamine affects blood pressure medicine

Guest Author: Phil Koerner, PhD. The U.S. Food and Drug Administration (USFDA) and The European Medicines Agency (EMA) have set legally-binding limits for nitrosamine impurities in sartan blood pressure medicines. Continue Reading

Tagged blood pressure medicine,EMA,FDA,genotoxic nitrosamines,Hetero Labs,HPLC-MS/MS,Nitrosamine,pioglitazone,sartan,sartan drugs,SCIEX,The European Medicines Agency,U.S. Food and Drug Administration,USFDA

FeaturedFun ScienceLiquid Chromatography (LC)Our CompanyPharma / Biopharma

Powerful Analytical Solutions for Biotherapeutics Development and QC

February 28, 2019February 28, 2019 Science UnfilteredLeave a comment

A look into biotherapeutics development and QC testing in the pharmaceutical industry.

A transformation in the pharmaceutical industry has occurred in the past few decades due to the advancement of biologics as therapeutic agents. What is less often discussed is a similar Continue Reading

Tagged Analytical Chemistry,analytical development,analytical methods,analytical solutions,biologics,biotherapeutics,biotherapeutics characterization,biotherapeutics development,bioZen,chromatographic method,Clarity OTX,DMPK,EMA,FDA,ICH,International Council of Harmonisation,Mass Spectrometry,monoclonal antibodies,monomeric protein,MS,N-glycan,native protein,oligonucleotide,pharmacokinetics,PK,protein analytical development,QC,SCIEX

FeaturedFun SciencePharma / Biopharma

LC-MS/MS Method for Determination of NDMA and NDEA in Valsartan

November 20, 2018November 20, 2018 Science UnfilteredLeave a comment

By: Philip J. Koerner, Ph.D. – Global Industry Manager – Pharmaceutical The Korea Food and Drug Administration (KFDA), in cooperation with SCIEX Korea, has recently published an official LC-MS/MS method using Continue Reading

Tagged 2.6 µm 100 x 3.0 mm,Candesartan,Diovan,EMA,European Directorate for the Quality of Medicines,European Medicines Agency,GSMS Inc.,heart failure,high blood pressure,human carcinogen,hydrochlorothiazide,hypertension,Irbesartan,KFDA,Kinetex,Korea Food and Drug Administration,LC-MS/MS,Lorsartan,Losartan,losartan potassium,N-nitrosodiethylamine,N-nitrosodimethylamine,NDEA,NDMA,Olmesartan,Sandoz,sartan,SCIEX,tetrazole,Valsartan,Westminster Pharmaceuticals Inc.

FeaturedHumanity in ScienceLiquid Chromatography (LC)Pharma / Biopharma

Metabolomics and Autism: Can Cross-linked Polyamine HPLC Columns Change Lives?

April 19, 2018August 14, 2018 Science UnfilteredLeave a comment

Chromatography has the ability to impact lives more than many think. Brian Rivera discovers this through his pursuit for more autism research for his son, Micah. By: Brian Rivera, Bioseparations Continue Reading

Tagged ASD,autism,autism awareness,autism research,autism spectrum disorder,CDC,Chromatography,Danaher,High Performance Liquid Chromatography,High Pressure Liquid Chromatography,HILIC,HPLC,HPLC Column,Hydrophilic Interaction Liquid Chromatography,Luna,luna omega,Metabolites,Metabolomic,Metabolomics,microflow Lc,pfas,SCIEX,UC San Diego

FeaturedLiquid Chromatography (LC)Technical Tips

What is Bisphenol A (BPA) and How Does It Affect You?

March 15, 2018 Science UnfilteredLeave a comment

[sg_popup id=”39″ event=”onload”][/sg_popup]By Scott Krepich, Food and Environmental Application Scientist The chemical bisphenol A (BPA) is used in the production of some plastics, many of which are utilized in water Continue Reading

Tagged Acetonitrile,AOAC,Biphenyl,Bisphenol A,BPA,Cancer,FDA,Food and Drug Administration,hydroxy groups,Kinetex,Kinetex Biphenyl,phenyl phases,plastics,QuEChERS,SCIEX,Sciex Turbo V

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Mass Spectrometry Tutorial: Tuning Analytes

January 18, 2018January 18, 2018 Science UnfilteredLeave a comment

When visiting scientists in their labs, Field Applications Scientist, Danielle Moore, is frequently asked about tuning their analytes on a mass spectrometer. More specifically, why it is so important to Continue Reading

Tagged Analytes,Data,LC-MS/MS,Mass Spec,Mass Spectrometer,Mass Spectrometry,SCIEX,SCIEX 4500,Tuning

Liquid Chromatography (LC)Pharma / BiopharmaTechnical Tips

The Effects of Changing Column Inner Diameter on LC-MS Applications-Part 4

August 29, 2017 Science UnfilteredLeave a comment

Part 4: Putting Our Interpretation to the Test Guest Author: Dr. Jeff Layne Welcome back to our final installation of this blog series on the effect of column inner diameter Continue Reading

Tagged Analytes,carbaryl,Column Inner Diameter,dimethoate,lc-ms,Pesticides,SCIEX,thiamethoxam

FeaturedLiquid Chromatography (LC)Technical Tips

The Effects of Changing Column Inner Diameter on LC-MS Applications- Part 2

July 27, 2017February 26, 2018 Science UnfilteredLeave a comment

Part 2: Changing Column Inner Diameter with Constant Flow Rate Guest Author: Dr. Jeff Layne Welcome back to this article series on the effects of changing column inner diameter on Continue Reading

Tagged Column ID,Column Inner Diameter,Flow Rate,Kinetex,LC/MS,SCIEX