The Importance of a Well Prepared Mobile Phase Explained

mobile phase buffers

Guest Author – Helen Whitby, PhD A buffer is an AQUEOUS solution containing a weak acid and its conjugate base (or a weak base and its conjugate acid). The pH of a buffer solution changes Continue Reading

Mobile Phase Preparation – Steps to Take for Ideal Analysis

components of mobile phase

Guest Author – Technical Expert Genevieve Hodson Liquid Chromatography is reliant upon a accurately made mobile phase. Many chromatographic problems can be attributed to an incorrectly prepared mobile phase. Contamination Continue Reading

Google Honors Danish Biochemist Responsible for the pH Scale – SPL Sørensen

Google Doodle honors pH scale

Søren Peder Lauritz Sørensen or S.P.L.  Sørensen, was a Danish biochemist who is most known for his introduction of the pH scale in 1909 while studying the effect of ion Continue Reading

Solid Phase Extraction & In-Well Hydrolysis for Analyzing Abusive Drugs

solid phase extraction analyzing drugs of abuse

The increase of testing drugs of abuse radically defines the workload for many laboratories, requiring testing methods to be accurate, reliable, and quick, which is where In-Well Hydrolysis and SPE Continue Reading

What the HILIC is HILIC?

Hydrophilic interaction liquid chromatography (HILIC) is a chromatographic mode used mainly for the separation of polar compounds that are too hydrophilic to be retained in a reversed phase column.

The Proof is in the Litter: How an Innovative Product is Saving Feline Lives

Many pet owners can tell if their furry friend is sick just by looking at them. What if there was a possible diagnosis lurking in your cat’s litter?

Technical Tip: Principle HPLC Conditions for LC/MS

High-performance (or pressure) liquid chromatography, more commonly known as HPLC, can be a useful tool to assist in the improvement or simplicity of mass spectral detection and analysis.