Easy Installation of Phenomenex UHPLC Columns onto Waters® ACQUITY® UPLC® Systems

Installation of Phenomenex column on Acquity system

Did you know that Phenomenex LC columns are a universal fit for all HPLC and UHPLC systems on the market? It’s simple to install Phenomenex UHPLC columns onto Waters® ACQUITY® UPLC® Systems. Here’s how! 1. Disconnect the pre-column heater from the oven. 2. Separated the front and back nuts so Continue Reading

Can an UHPLC Column Have Too Much Efficiency?

Is 100% aqueous stability and unique polar selectivity not enough to convince you to try Luna Omega? Well, here is another equally-compelling reason Guest Author: Dr. Jeff Layne You Can Never Have Too Much Efficiency! The efficiency of a column is a measurement of the amount of band broadening that Continue Reading

A Comparison of Various Core-Shell C18 Phases for Method Development

When performing reversed phase LC separations, there is a natural tendency of method developers to reach for the most commonly used phase—a C18. However, there are so many different variations of C18 phases available to method developers that it often becomes difficult to choose a C18 column that one had Continue Reading

Selectivity for Polar Acids

Guest Author: Dr. Jeff Layne Is super-high efficiency and 100 % aqueous stability not enough to convince you to try Luna® Omega UHPLC Columns? Well then, how about a unique selectivity for polar acidic molecules? Selectivity for Polar Acids is Sweet! Developing robust methods for the analysis of small, polar Continue Reading

Sitting with Scientists: A Godfather of UHPLC- Dr. Jason Anspach

Meet one of the developers of UHPLC, Jason Anspach, Ph.D.- Research and Development, Senior Scientist here at Phenomenex. Ever read about advancements in science and wonder where and how it all started? When it comes to developments in Ultra High Performance Liquid Chromatography (UHPLC), Jason Anspach doesn’t have to wonder, because he was Continue Reading

Jeff Tries Cannabis Part 6: HPLC Method Development

Guest Author: Jeff Layne Well – it seems that we have a little more work to do with cannabis potency testing. I had originally planned to have the last article be the last of this HPLC method development series, however, we had a request to develop a similar separation using Continue Reading

Selecting the Right Column for Your Reversed Phase Method

Selecting the right column for your reversed phase method isn’t always easy. We wanted to help in the decision-making process by breaking down the different steps you’ll need to consider when selecting your column. For a full in depth look into the selection process see our Ultimate Guide to HPLC/UHPLC Continue Reading

Webinar Highlights – UHPLC: Small Particle Solutions for Big Chromatography Challenges

Senior Field Application Scientist Scott Krepich answers your questions on UHPLC column selection and shares industry-specific tips In this free webinar, Scott Krepich, Senior Field Application Scientist, Phenomenex Inc., gave an informative presentation on column selection for UHPLC and shared industry-specific tips on method screening and development. Read on for Continue Reading

Symbiosis of Core-Shell and Fully Porous Particles: Implementing Both for Better HPLC and UHPLC Results

(Via LCGC North America) Learn to capitalize on the advantages of both core-shell and thermally modified fully porous stationary phase media to expand the options for HPLC and UHPLC method development. High performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography(UHPLC) method development options can be extended significantly by tapping Continue Reading

What is HPLC and How Does it Work?

Phenomenex HPLC Columns

Guest author: Dr. Ramkumar Dhandapani Chromatography is coined from the Greek word chroma- which means color and -graphein which means to write. First recorded use of column chromatography can be traced back to Russian scientist Mikhail Tsvet who crushed calcium carbonate into a tube and added homogenized green plant leaves Continue Reading