Steps to Properly Program Your Claricep Flash Column on an Rf Instrument Having trouble getting your flash column to connect with your ISCO CombiFlash® Rf Instrument? Keep getting the same Continue Reading
Core-Shell Technology Improves HPLC Methods Within USPFeaturedLiquid Chromatography (LC)Pharma / Biopharma
Using Core-Shell Technology to Improve HPLC Methods within USP: Part 5
Guest Author: Dr. Jeff Layne Part V: Some Final Points on the Chromatographic Impact of Making Adjustments to Existing Methods We are finally coming to the end of our series, Continue Reading
FeaturedLiquid Chromatography (LC)The Effects of Changing Column Inner Diameter on LC-MS Applications
The Effects of Changing Column Inner Diameter on LC-MS Applications-Part 3
Part 3: What is the Best Column ID for You? Hi, and welcome back to the third installation of this article series on the effect of changing column inner diameter (ID) Continue Reading
FeaturedLiquid Chromatography (LC)Technical TipsThe Effects of Changing Column Inner Diameter on LC-MS Applications
The Effects of Changing Column Inner Diameter on LC-MS Applications- Part 2
Part 2: Changing Column Inner Diameter with Constant Flow Rate Guest Author: Dr. Jeff Layne Welcome back to this article series on the effects of changing column inner diameter on Continue Reading
FeaturedLiquid Chromatography (LC)The Effects of Changing Column Inner Diameter on LC-MS Applications
The Effects of Changing Column Inner Diameter on LC-MS Applications- Part 1
Part 1: Changing Column Inner Diameter While Adjusting Flow Rate Guest Author: Dr. Jeff Layne Welcome everyone! Jeff Layne here, back with another article series, and this time we are Continue Reading
Technical Tip: Column Loadability
Do you ever worry about your column’s loadability? Do you find yourself Googling, “How much am I able to load onto XYZ phase?” Ever fret over this issue so much Continue Reading
Best and Worst Organic Solvents to Use in LC
There are several critical characteristics to take into consideration when choosing the appropriate organic solvent to use in liquid chromatography. For example, high viscosity solvents may produce backpressures that are too high for the HPLC system used.
Humanity in Science: Combating Counterfeit with Capillary Electrophoresis
The Humanity in Science Award was created in 2015 to recognize outstanding developments in science that could change human lives for the better. There were many runners-up who did (and do!) amazing things for humanity. Recently, The Analytical Scientist sat down with each of them to catch up, and find out how their ventures have progressed in the last 12 months.
Technical Tip: Principle HPLC Conditions for LC/MS
High-performance (or pressure) liquid chromatography, more commonly known as HPLC, can be a useful tool to assist in the improvement or simplicity of mass spectral detection and analysis.
Technical Tip: Backpressure
Scientists aren’t perfect. Nobody is. In our Technical Tips, we can solve your most debilitating issues—from hardware to methodology—together.